Which of them can be used for a variety of affections? VAT Number: GB 133 4845 18, All Content © Riaflex Limited NOTE:  However, once in the body, they both achieve the same results. Also, a study in 2013 linked glucosamine sulfate with an … Hi Dave, do you mean combining glucosamin HCl and MSM versus glucosamine sulfate alone? Glucosamine HCl does not. Glucosamine Sulfate vs Glucosamine HClWhile most published research has been done using glucosamine sulfate, the studies using glucosamine HCl have yielded similar results. Enter your ID now for these enhanced features. Glucosamine hydrochloride does not contain sulfate. That’s because the sulfur rebuilds cartilages and promotes their loss in the future. That fact alone will now enable vegetarians and people with shellfish allergies the opportunity to use our formula. The highest possible rating you can get is “Effective,” and according to discussion of its ratings by the National Institutes of Health, it’s “likely effective for osteoarthritis.” And osteoarthritis is the most common form of arthritis that causes knee pain. One of the discussions you may have researched would be taking glucosamine sulfate vs glucosamine HCL (hydrochloride). So it’s important going with a brand you can trust. Safety. Arthritis is a growing health problem and a common cause of disability in many industrialized countries, including the United States. There is no evidence to suggest that glucosamine sulfate offers advantages over glucosamine hydrochloride. To give you an idea – the common pain-killer paracetamol is marketed under more than 50 brand names! But after reading these aspects about the 2 forms, I think you can tell the difference. We then went forward with a full-scale, double-blind, placebo-controlled intervention trial with glucosamine hydrochloride, the results, of which, are published in the Journal of Rheumatology listed in the references on the next page. Setnikar L, Palumbo R, Canali S, Zanolo G. Pharmacokinetics of glucosmine in man. Do not confuse these with Glucosamine sulfate. To be honest, I can see a big difference between these 2 forms. Effect of treatment of glucosamine hydrochloride in the treatment of pain in osteoarthritic of the knee. In light of the increasing number of alternative therapies and ‘me-too’ drugs to treat a disease, it becomes important to know which is the best drug available in the market. A close look at the study shows that, in actual fact, half the subjects were shown to benefit from glucosamine hydrochloride with the placebo response almost as positive. It may keep osteoarthritis from causing as much harm as it possibly could. However, glucosamine sulfate consistently outperforms glucosamine HCL in studies. Glucosamine Sulfate vs Glucosamine HCL. That’s totally right, but the HCl form doesn’t have any sulfur inside. While most published research has been done using glucosamine sulfate, the studies using glucosamine HCl have yielded similar results. In addition, commercially available glucosamine sulfate is glucosamine HCl with 2KCl (potassium sulfate) added to the mixture. You find glucosamine sulfate naturally in your body, and it can be found in places in nature like the shells of shellfish, Your body uses it to build the cartilage and fluids that surround your joints. I’ve tried it myself, and it’s the substance that helped me most. After all, they’re both. De meest gebruikte zijn glucosamine sulfaat en glucosamine … One common dilemma is over the two forms of glucosamine available in the market which are glucosamine sulfate and glucosamine HCl (or glucosamine hydrochloride). In addition to this we only use pharmaceutical grade Glucosamine which is 99% pure to ensure the highest possible yield of active Glucosamine. After absorption, the sulfate ions enter the blood stream where a steady level already exists. Comparable clinical outcomes between glucosamine sulfate-potassium chloride and glucosamine sulfate sodium chloride in patients with mild and moderate knee osteoarthritis: a randomized, double-blind study Background: Glucosamine sulfate has been recommended for treatment of knee osteoarthritis in several published guidelines. Trademark number: 2456091 We first conducted pilot testing, which indicated benefit for those with osteoarthritis. Now – when I wrote this article, I tried to find references for what I was saying. Which of these forms is better? Er zijn verschillende vormen van glucosamine. Glucosamine HCl: These tablets overcome the shortcomings of glucosamine sulfate tablets. Your email address will not be published. Glucosamine Sulfate: The main problem with glucosamine sulfate tablets is that they need to be additionally stabilized using either sodium chloride (NaCl) or potassium chloride (KCl) salt. Both the drugs are used to treat osteoarthritis. Your email address will not be published. The pH of a fluid is also what dictates whether a particular substance will dissolve in it or not. Which of these forms has a higher purity? Here’s how it works: When the link is clicked, a cookie (if allowed) is created. On the other hand, I don’t really get an effect with glucosamine HCl. A study (Setnikar et.al. The main difference in the two drugs is explained below –. Read our article and understand the differences so that you can decide which form is most suitable for you. Required fields are marked *. I don’t know if it’s just me or not, but, My OA pain isn’t very bad, so most supplements can help it. Clin Ther 1980;3:260-72, Pujalte JM, Llavore EP, Ylescupidez FR. Hydrochloride offers a more concentrated form of glucosamine. *These statements have not been evaluated by the F.D.A. It is here that the tablet needs to dissolve without the actual active drug molecule being hampered. Which one do most supplements use? If you want to combine glucosamine with MSM, you can do it with any of the forms. However, apart from the above glitch, a comparison between the therapeutic effects of the above two forms of glucosamine reveals no significant difference. A number of glucosamine products tout the inclusion of chondroitin, a cattle-sourced compound, as a necessary and beneficial addition to glucosamine products. Glucosamine sulphate has to be stabilised with sodium chloride (salt) or potassium chloride, and this can be as much as 30%. Powered by  - Designed with the Hueman theme, Glucosamine is probably the best ingredient for osteoarthritis. Shopping buttons on applicable product pages will appear to the referred user. It also continues to discuss that “some research suggests that glucosamine reduces pain of osteoarthritis in the knee” specifically. Maybe they have for years and have gotten progressively worse from the…, The phrase “living with knee pain” can mean different things to different people. It could well be only in your head, if you think one of the forms gives you better relief! As part of sports nutrition study, a group of athletes took either 1.5 or 3g glucosamine per day.

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